Do all morphs have diffrent personalities?

[asplundii]

And yet I've been told first hand by the people that have bred more spider combos than any one that they have seen normal spider sibs that wobble.

"Wobble" can happen in any morph and it is not necessarily associated with spider breedings. I saw a lesser spinning it's little head off at a show and actually asked the guy if it was from a spider clutch and he said no but I was the third person to ask him that.

I have never heard the information you posted, based on your "more spider combos than any one" I can take a wild stab at who you are referring to and if I am correct then I guess I should not be surprised I have not heard this info before... So, now there may be cases with this one breeder, where spider and "wobble" have been un-linked. Are there others? (Not saying there are not, I just have this thing about a sample size of 1...)

I never said replace it I was implying strengthening the gene by adding in something genetically that its lacking that causes the wobble.

I apologize if I am sounding dense here but how can you "strengthen the gene" without adding the gene itself back in?

Then if this is 100% true and the spider gene is the only reason for wobbling then it puts to rest the idea that there are spiders that don't wobble

.

Like the Jag carpets this is asking to prove a negative which cannot be done. Spiders that are not "wobbling" today may well "wobble" tomorrow, or next week, or next year... Or never if the proper stress event does not trigger them.

Again I never said every morph has some curative effect I never said that any morph had a curative effect.

I apologize if I misread but you seemed to be supporting the statement made early in the thread:

Adding the spider gene to a combo morph seems to strengthen it and reduces the frequency of wobbles appearing in combos vs. the spider gene on its own.

That is making a blanket statement that morphs in general are a cure all for "wobble". I disagree with that statement. I do not think morphs make any difference, spiders will "wobble" if they are normal or albino or bee or what ever...

But you can't deny that there are things in the gene's of these animals that we don't understand. So to say that it isn't out there also isn't true.

No I cannot deny that there are things in the genes of these animals that we do not understand. But I would follow that up with the caveat that snakes are not some genetic black box and what happens in one type of animal quite likely happens in another cause that has been show to be the case. So what we know about mutant phenotypes in other animals can give us a pretty good idea what is going on in our snakes.

So your saying that by adding addition working copy's of genetic code in to the DNA of the animal the defective gene can be corrected, not eliminated but corrected in that individual?

No. I am saying that if you take something like cystic fibrosis, which is recessive so a person suffering from it has no functional gene, and add a WT copy of the gene in to the appropriate cells, then you can correct the defective phenotye in those cells. You do not correct the defective gene, it is still there and always will be (for the time being anyways cause we do not have a technology that can rewrite the DNA in every cell of a body.)

By this same token, you cannot use gene therapy to "cure" sickle cell because the mutant allele is dominant. No matter how many normal copies of the allele you introduce you will still have the mutant being expressed and exerting its effect.

I can see how possibly some genes are redundant or close to redundant. For example, the spider morph and the pinstripe morph have a lot of similarities, even though they are on different loci. So maybe whatever those genes do, it is similar and possibly somewhat redundant. However, in that case, I would expect a spinner to be MORE likely to have problems with wobbles, rather than less. A normal, spider, pin, and spinner all have a total of 4 genes on those 2 loci. So a spinner doesn't have "more" genes; the only thing it has more of is mutated genes. Why would the pinstripe gene do a better job of filling in that gap in the allele (which I still don't really know what you mean by that, so forgive me if this makes no sense) than the normal gene on the pinstripe allele does? If anything, I would think that since the spider and pinstripe morphs have similarities, that a spinner would wobble MORE than a regular spider, because it has less normal genes, and more mutations.

You posit an interesting idea there KC. Just because the spider and pin (and woma and GRP) are similar in phenotype they are not necessarily similar in genotype. Off hand I can think of a few different ways to alter pattern that are not genetically related so there would be no shared function between them and you would not therefore see any cumulative effect.

And as far as an apparently totally unrelated gene, such as pastel, helping, I just don't see why or how it could. You said scoliosis is genetic in people, so I'm going to use that example even though I don't personally know if it is or not. Assume there is some sort of genetic therapy to treat scoliosis in people where they give a person a pill with some extra genes (again, I don't know if there is or not, and I don't think gene therapy is really just a pill, but simplifying in order to make a point). Do you think that what they do is put genes for blue eyes in that pill? Or give them normal copies of the gene of which they have a mutated version that causes the scoliosis?

Yes, this is the point I was trying to make. You blue eye genes (pastel) is not going to fix the mutation of scoliosis (spider)..