Absolutely! Over the years that I have kept snakes I have been twice sent a snake with mites. The first one was early on and I had little experience. I picked up a lice treatment used for humans at a drugstore (on the advice of an experienced keeper) and used it with success and no ill effects that I am aware of. The second time I used Reptile Relief because I had no PAM at the time. The Reptile Relief worked for right around a month and then the mites were back. I used it again and ordered PAM and never saw another mite. This discussion isn't about what I choose to do as an experienced keeper in my collection. It's about what I choose to recommend to people that are new to the hobby like I was back then. I would feel horrible if I told someone to use a product not made for treating reptile mites and the person's snake died. I don't need that on my conscience. Also, I know for a fact that the residual effect of PAM isn't something available in those other products. As an aside, of course strict quarantine methods are key. They can be the difference between one snake with mites or your whole collection with mites.