I just wanted to share my experience I had today with p.a.m... I had 4 young boas that got mites from a roommates snake he brought in...(he's not very keen on quarintine..) anyway, I treated the tub last night, and let it dry for about 4 hours outside. We didn't put down any substrate, and only gave them a water bowl. I checked on them this morning, and same thing: they were all convulsing, twitching, yawning, flipping over, etc. They had no control over their bodies, or bowel movements. We immediately took them out of the treated tub, wrinsed them off and pit them in clean tubs. The twitching slowed down, but is still there. We called p.a.m. and they.said that this is a rare occurrence, but that it is possible for the snakes to get neurological problems. They said that the p.a.m. attaches to the brain stem, and the brain "tells" the heart and lungs to stop working, and that's how it kills the mites. They said the next 48 hours are crucial, and that the snakes may live or die. They said at this point, there is nothing a vet can do, and that we have to wait and see what happens...I'm super angry about it...I may lose 4 boas because of this. They also said that if the snakes live through this, that they may or may not twitch for the rest of their lives... Maybe they should pit something on the side of the can about possible side effects..