Quote Originally Posted by jknudson View Post
It is generally referred to as "line breeding". Reptiles can handle several generations of inbreeding before as such deformities could/would show up.

Many of the morphs we know and love were started from a few single specimens, and to prove them out line breeding was used. After all the work is done to figure out the genetics, it isn't a bad idea to out-cross the animals to non relative individuals to help restrengthen the lines, and create more genetically diverse animals.

So really, no you do not have to worry about it.
Even for rats?