Yes, there are medical conditions that make it extremely difficult to lose weight. I have hypothyroidism as well. I decided to try and lose that last bit of weight (inspired by all you wonderful people on the weightloss thread) and joined a gym. I work out 5 days a week for 1.5 hours a day. (in fact when I missed going this past week while I had the flu, they called to check up on me) I usually do 30 minutes cardio, followed by a class that rotates weight lifting, yoga, pilates, and cardio. I have not lost a single pound in 6 months. So yes, weight loss is not all about food and exercise for some.

I find it very hard to judge someone without knowing what they've tried or what they've been through. Not to say that it's not easy to make that sweeping judgement at first glance, but I try not to.