You say that as a joke, but I know dogs that really do have to be tranquilized even for nail trims, and it's ridiculous. These 8lb Chihuahuas run the house. I'd be embarassed to be that owner, you know?
I have a poodle in foster care with me right now who was a biter like that, and he quickly learned that's not a successful technique anymore. There's no reason to let them get away with it. It's certainly not "cute" when you can't handle them safely.