i Handle both of my for at least 4 hours a day. i do this religiously. i dont hold them for 4 hours strait though. that would stress them out alot. and i dont hold them a day after they feed either. i use carefresh bedding for both of them. not the carefresh ultra though. it smells really bad and looks like theyre crawling aroung in popcorn. i just use the normal brown carefresh. it looks natural and smells really nice. hope this helps.