of course it is possible but i think this largely comes down to maintaining strict protocols and learning how to properly read the animals - the only envenomation i have ever received wasn’t from my collection but from a wild adult female black widow because i stupidly didn’t shake out my outdoor shoes - it’s entirely possible to go through your whole keeping career without ever being tagged by arachnids if you observe strict safety protocols that i assume would be similar to that of hot/big snake keepers
also comes down to not doing stupid stuff imo eg: putting a big snake around your neck, purposely creating negative experiences to get “cool” striking pix, etc - the more i go on this journey and the more i think on it - a lot of negative things i think could be avoided