You shouldn't have a problem! I keep mine in my bedroom because I live in a pretty small apartment and prefer to keep my cat closed off from the room they're in. Never been an issue, and aside from a few occasional shuffling noises I rarely hear them at all. I'm rarely ever in my bedroom at all during the day, though; if your bedroom is a more active area of the house you might want to take steps like covering the enclosure with a blanket to minimize the possibility of disturbing or stressing out the snake.