I'm so sorry about the loss of your geckos. IBD (inclusion body disease) comes to mind, but I don't know if it affects lizards too, or how, if it does. I'm sure there's others too.
Try this: (skip down to "Diseases") https://www.vetfolio.com/learn/artic...tile-clinician
And pay attention also to toxins.
Are you sure your BP hasn't always had pupils of a different size? And maybe you just never noticed? Do both pupils respond to a narrow-beam flashlight in a dark room, or to bright sunlight?
Exposure to excessive heat can also cause neurological damage, but I hardly think that ALL your animals would be affected- to me, that suggests something contagious, I'm sorry to say.
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