I've only kept this one Spotted python, & never a Children's python, but some have talked about a challenge getting the tiny Children's python hatchlings to feed well,
so that's one slight advantage (IMO) for the Spotted python...they're a little bit larger than Children's, so the hatchlings would generally be easier to get going, but either
way you'd want to get one that's well-started with a feeding record for best results, & of course that goes for ANY kind of snake. The Spotted hatchlings are from 9 to
13", whereas a Children's starts off between 8.5-10.5".