One of the first things I've done was wall off the back and sides of the tank with dark paper(on the outside) made sure the top was covered at the appropriate amount for optimal humidity levels and made sure there was enough places she could hide around in. A lot of clutter. Things like that, when I swapped her over out of quarantine.
The only reason I change water daily is because I de-chlorinate it with reptisafe. So far I haven't really noticed a difference in between the snakes drinking it or not so I'm probably just gonna go back to regular old tap water. I change it every three days or so in that case if it's just regular old tap water, not de-chlorinated tap water.
As for handling, I handle her between 15 minutes to an hour. I usually sit down and watch a few youtube videos with her, let her roam about on my arms, the couch. She generally likes to try and make me take off my glasses when she scopes about my head. She's curious and generally likes to explore. I usually try to handle her every 3 days or so. I leave her alone for two days after I've fed her for obvious reasons.