I highly recommend hook training. Before you reach in and grab him just rub him with a snake hook (or something similar) to make sure he's awake and let him know you're there. Then just keep the hook between his head and your hand and reach in and gently lift him out of his enclosure. Generally, most snakes aren't going to bite once they're out of their enclosure unless there is a sudden fast movement or something that startles them. Most snake bites are going to happen when you initially reach in to pick them up, but they will be fine once they're out. I'm sure there are nippy Ball Pythons just like any other species or any other kind of animal, but generally you don't have much to worry about with Ball Pythons. They are much more docile, shy and timid and less "aggressive" than most other species.
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