I can't really speak to this one as I do not use it in my caging.
I would highly recommend HDPE, or more specifically, seaboard/starboard HDPE. The materials is FDA/USDA ceritified, UV stable, and non-porous (makes cleaning much easier and staining is greatly reduced). It is more expensive than PVC, but better in most respects.
Some people still do, but given that t-slot construction is more expensive and not necessarily for a structurally sound cage, most deem it not worth it. Reptile edge still makes cages akin to t-slot as well as Dragon Stand. I admit they look nice, but look like the seams would be difficult to seal.









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