As long as there are tight hides, then big cages are fine. The ONLY problem with large enclosures is keeping them heated. The larger size, the more energy needed to heat it. For example, unless the room you are keeping the python in is 84F all the time, you will need a large under/tank-heater and some way to keep the ambient temps up.
I also use very large storage tubs for my pythons. I use a strip of 6” wide heat tape on one end and an infrared space heater to keep ambient rack temps up.