No even with a reliable T-stat something can go wrong just like it can with any heating devices however it is rare, the best you can do is make sure you have a reliable thermostat, make sure not to use cheap power cord (some people do) and back up your t-stat.
And yes I had an issue and while I thought the T-stat was at fault it turned out that after testing it was not, there was an issue with the heat tape itself (which was properly installed, recessed and ran without issue for 3 years prior), the results were one melted tub and nothing more since I use PVC rack which is fire resistant.
When dealing with electrical and heat devices there is ALWAYS a risk but again it is rare.
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