I would think that snake could eat large or jumbo mice, no problem. How do you prepare your frozen mice? Whatever you do, don't boil them LOL. I just watched a YouTube video on how to boil your rodent to prepare it for feeding LOL. Personally I would set it out at room temp until it's completely thawed (but no longer), then warm to 100-110F using an incubator, lamp, or warm water. And I like to feed late at night, my snakes won't eat early in the AM.