I've mentioned in the past that I will not own or work with the spider gene because of the wobble. I do not condemn those that wish to do so but I can't in good conscience do it myself.
If I were to put it in relative human terms, I've never met a person with Down's Syndrome who wasn't sweet, gentle, compassionate, and for the most part very lovable. A world filled with people whose dispositions where like that, would probably be a nicer world. But there are clearly deficits when we examine the whole being. It would be self indulgent and irresponsible for me to ignore those deficits and produce people with the syndrome, just to reap the characteristics I desire.
As hyperbolic as my example may be, we don't/can't really know what's going on with snakes that carry the spider gene beyond what we see. To assume the animal is fine because it lives, eats , and poops is cavalier. Please be reminded that people with Down's Syndrome live, eat, and poop. This is just my $0.02.
I shall now run for cover while you light the torches and grab the pitchforks.