I would think that with a larger rat you could go longer between feedings. I'd try it, some snakes will refuse it if you get too big. My reticulated python is on super jumbo rats LOL. (520 grams) For my ball pythons I go with as large as they will take, usually because I raise my own and have an excess of rats, I try to feed off the largest ones first so I don't get too many jumbos.
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