I don't believe you can compare keeping large constrictors to keeping a tiger... under proper care and knowledgeable handling I see no reason why they should be under strict regulation. As someone mentioned before, throwing the large constrictor keepers under the bus is exactly what HSUS wants. If there are strict regulations on them and they have to be inspected... very few people will keep them and the large constrictor hobby will begin dying out.
Now I am not saying there should not be SOME regulation about it. In tropical areas like Florida, I can see the sense in having to obtain a permit (it shouldn't be too difficult to get though) and microchip your animal to ensure no impulse buyers get into a retic or burm with no prior research.
Also, if you are worried about an adult human getting eaten by a large constrictor it leads me to believe you do not know much about them.
The "killer snake" stereotype is exactly what we are trying to debunk... not propagate.