Last time I checked there were also mites, parasites, predators, natural disasters, and all sorts of other awesome things in the wild. Maybe I should be attempting to recreate these things in my snake room too! One of my biggest pet peeves is using "the wild" as primary justification for doing or not doing things like this in our private collections - especially when it comes to innane decisions about whether or not to use a simple product.
Also, last time I checked, ReptiSafe is made by ZooMed, not a big box store. You can find the stuff everywhere. While it may not be necessary in this instance, there is certainly a place for it in the hobby (which isn't to fleece one over on us, I assure you).