Identified problems:
Your ambient is too low.
You are running a heating device without knowing what basking temp it is providing.
Your snake needs to see a vet...it could have a burn, it could have rot, it could have something else.
You are running an unregulated heating device.
You are running a heating device that is probably incapable of meeting the thermoregulation requirements for a ball python.
Your ambient is low and your humidity is fairly high...more on that later.
The fact that a couple of key husbandry issues are screwed up probably means that there are a few more that need attention. However, you have provided little information in your post. What is the hot spot temp? What type of enclosure is he in? How are you providing humidity?
Now a couple of people are going to chime in here - many opining on what they ASSume is the problem. I am not a vet. They are not vets. With the humidity as high as you describe, the ambient as low as you describe and the fact that you are running an unregulated heat source means that you need to not only see a vet, but dial all of your husbandry parameters in.
Ball pythons use a heat pad/UTH to thermoregulate and raise their overall body temperature. When you keep the enclosure too cold, you are forcing that poor animal to spend more time on the heat source...a heat source that is unregulated. You are therefore providing him with a prime opportunity to injure himself - possibly with a burn.
On top of this, the humidity you describe is fairly hard to achieve with such a low ambient temp, which would lead me to believe that your humidity delivery system may add to the unhealthy environment you have already described. When you combine high humidity via misting, spritzing, etc, with a burn or damp and cool ambient conditions, you are providing that snake an opportunity with a chance to pick up rot or a bacterial infection.
While you are making your vet appointment and ignoring all of the people who will give you armchair guesses as to whether there is an issue or not, or what the issue is, you need to check the care sheet on this Forum and provide as close to the prescribed parameters as possible. This will involve spending money on thermostats, secondary heating sources, hides, etc.
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