1. Remove snake
2. remove decorations. Check all decorations for poop/pee. Clean where needed.
3. Using a plastic glove, put all substrate into a plastic grocery bag. (Or pick up the tank and dump it all into a trashcan. My tank is too big to do this)
4. spot clean any places where substrate has been stuck to glass by pee/water.
5. spray and wipe down entire tank with plain warm water.
6. put fresh new substrate/decorations/thermometer probes/exc….
7. Return snake to its home.

This is how i do it, but I only have one snake. There might be a more efficient way with tub systems, or multiple snakes.