I really love my scales. They are smooth, they are shiny looking and they are natural feeling and sort of have that taboo aggressive looking touch- at least to the people who don't know snakes very well. I love Brian B. a lot and BHB. But I have seen older scaleless adults and I don't think they are nearly as impressive as fully scaled adult comparatives. I think it was a break in history, yes. I think he deserves tons of kudos, yes. But I will never want one, I don't think or breed them. But it was a very big feat. So I will give him that.
As far as disease and what not, I really don't think it will progress that far into popularity. Hopefully not anyway. If it does then yes, I would really worry about it. But I am betting that it won't.
*Scaleless adults meaning other scaleless species- NOT ball pythons.