The active ingredient in Frontline is called fipronil. Just doing a google search on "fipronil snake mite" is enough to scare me out of using it as it appears to be more toxic to snakes than permethrin.
http://www.karingalvet.com.au/Pet-Ca...tile-Mites.asp
http://www.boa-constrictors.com/en/I...nt_snake_mites
http://www.repticzone.com/forums/Boa...s/1791835.html
Also, it does not seem to persist as well as permethrin-based products, so it won't affect any newly-hatched mites.
PAM is a 0.5% permethrin solution in an aerosol can. One 2-oz (59 ml) bottle of NIX/RID lice treatment (available at WalMart, CVS, Rite-Aid, etc.) mixed very well with 1 gallon of water also produces a 0.5% permethrin solution if you need to purchase something fast and don't want to wait to have the PAM shipped. You will need to get your own spray bottle, obviously one that has never been (and will never be) used for any other chemical product. Use it just on the enclosure, substrate (paper towels), and hides, and allow them all to dry completely before putting your snake back. Do not use it on the water dish. Some people spray their snakes with it, I do not as permethrin poisoning is a risk. Instead I treat the snake by soaking in water with just a drop of mild dish soap like Dawn (it drowns the mites per my vet) and/or with a product like Reptile Spray that is formulated to use on the snake. I just spray a paper towel and gently wipe the snake with it and let them crawl across it, and use a q-tip for under the chin, as most snakes hate getting sprayed.
Keep the permethrin bottle out of direct sunlight and it will be good for 30 days. I re-treat clean paper towels and allow them to dry before replacing soiled ones in the enclosure.
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