Very rarely is this is an issue in my experience, I placed my 2013 pastel in 106qt tub after getting her at a show, she ate seven days later and is continuing to prove hardy. Personally I prefer to give my specimens a bit more space than what is usually recommended (for example, the minimum size cage I use for hatchling BPs is 28-32qts simply because as long as I make that environment stimulating, I l know it will be used. I also understand the fact that the main thing deciding stress in Python regius is the availability of hides, as long as there are various hide spots within an enclosure, then any "excess" size is relatively meaningless.