Just depends. I had a Albino gal for years, and she NEVER missed a meal. Rain, shine, shed, she was always up to eat. So it just depends on the snake. I always offer anyways, because they can change their mind down the road.
With that said, if you are specifically thawing a rat for the one snake and they may refuse in shed, I would just wait till after the shed if there is no other snake to feed the rat to. (If that makes sense)
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