Mine actually doesn't seem to mind it very much. Granted Ive had him for 4 weeks and 2 were just spent shedding. I've found he spends a day or two just hangin out in one of his suction cupped plants once in a new environment, then when he gets used to it he goes in his hide and never comes back out hahah. I've not once had him hiss at me though when misting the cage (and I had to do it a LOT the past couple weeks) or changing the water, even while in shed. I think my guy is just scared by everything.. Never really defensive, though... Just a whimp. Today to really see how he felt about it though I actually sprayed the back half of his body with some tropical mist as he was mosying about his tank and nothing! Didn't even flinch.