I only have two snakes that eat live (rats) so the pros to me for feeding f/t is the convenience (just thaw em and feed) and I can buy in bulk whenever I need. I hear that mice are more dirty/smelly than breeding rats, so that makes it so I don't need to breed my own mice too (though me and my bf have some breeding rats for our own feeders). As long as you supervise the live feedings you shouldn't have any issues, keep a pen/something handy to stick in the feeder's mouth so it doesn't bite the snake (if you need to).
You can handle the snake before you offer, but I usually don't handle a snake a day prior to feeding so it doesn't stress out and possibly refuse a meal. That's only how I do it though, I've never heard of not handling a snake for three days before feeding.
Edit: Also, some say that feeding live/prekilled is more nutritious than feeding f/t, though I haven't seen any studies that 100% prove this and haven't seen it proven true for my collection.
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