the only city that could get me to leave D.C. at this point would be Austin, Tx. strong economy, decent weather (excepting July and August), and no shortage of nightlife or music. admittedly I am in the tank for Seattle, but only because I am firmly stuck in the early 1990s, and haven't heard all too many great things about living there.
good luck with your decision.
Nirvana was in seattle in the early '90s. There nothing bad about that!