I don't have to mist at all (during shed I have to but normally I do not)
I live in Florida so that plays a big role in it, The other main factor is the PVC cages that I use. The PVC cages hold in the heat and humidity very well and use Flexwatt or Radiant Heat Panels to provide the proper temperatures (neither kill humidity)
I use either corrugated wrap or paper towels for my substrate
I do have a automated misting system but I only use it during shed. (the misting system consists of a mist king pump/nozzle system and my Herpstat 4/ Herpstat humidity sensor)