In my experience it's much easier to get a mouse eater that's eaten a few rats back on mice than it is to get a rat eater that's eaten a few mice back on rats.
I'm going to have to say it depends on the individual. I bred a 3 year old, thick 1,200 gram female last year that gave me a perfect clutch of 4 eggs(I don't particularly mind small clutches). Her recovery after laying was miles ahead of any of my larger females on the same feeding schedule, and she has surpassed a couple of them in size(currently 2,000+ grams). She currently has 7-8 developing follicles...so I would say that if this were to be a continuing trend, she'll have no problem at all getting big and regularly dropping 10+ egg clutches.