The one and only AGRESSIVE snake I ever took in was only hungry. So I lean toward that a lot. What are you and what does he weigh. for a big guy like that I would recomend 15% of body weight every 7 days. Or if you are just going buy size get something a little bigger or move to feeding a litle more often. My Big girl 1300G is in the same room as the daughters pet rats and we have had no problems. She was the only agressive snake like I said earlier and well she would strike at anything in her cage. Moved her to small rats 1 every 7 days and now she is a real sweetheart loves to come out and hang with us watching TV as much as a snake can. The only other advice I would give is does he feel secure 2 tight fitting hides and 3 sides of the enclosure blacked out? I really hope this helps I am pretty sure its not rats being in the room with him