We usually give ours 48 after feeding before handling. If your ball is active, he might be stressed. A hiding ball is a happy ball. What is your set up like, and how old is the ball? If he continues to be "very" active, I would check husbandry. Make sure he has proper hides and temps. But as far as being lethargic goes, after ours eat we don't see them for a day or two, so totally normal. Welcome to bp, you can find tons of great info and help here.