No, my ball pythons have never shown any fondness for stimulation...their behavior indicates more stress when they're exposed to novel situations, or their routine is broken.

My Oscar fish, on the other hand, does appear to enjoy mental stimulation, and he's a riot to watch when you add a new decoration to the tank.

The only thing my ball pythons appear to enjoy is eating and breeding, alas. They also like fresh water. That's pretty much it.