Unfortunately I believe there is a user on here who did get bug-eyed babies out of a lesser x butter breeding. (That was actually one of the main things that convinced me that butter and lesser are the same thing ...) So it's not a guarantee, of course, but it is a possibility.
I don't believe it is due to inbreeding, and thus I'm not sure if outcrossing will get rid of it. I think that something about the blue-eyed leucistic trait itself causes various eye issues (wish I knew why, but I don't). Leucistic Texas rat snake are the most infamous example, but I think that the Lucy Burms may have some eye problems as well on occasion.
And honestly, this year I produced four lesser x mojave leucistics and out of four babies, three are perfect and one is indeed cross-eyed. Not bug-eyed, but cross-eyed. So maybe it is unavoidable.