Thanks to everyone that replied and voted! I'm really curious to see how this poll winds up, but I can definitely already see where it's heading.

I find it really fascinating that significantly more people are turned off by the potential for kinking in caramels than the (almost inevitable) neuro issues in spiders. I do have one male caramel and although caramel projects aren't a huge part of my collection by any means, I probably will keep forging ahead with them (mainly the caramel mojave stuff).

I guess maybe I'm still hopeful that selective breeding may eliminate or decrease the incidence of kinking -- unlike the spider neuro issues, it isn't a guarantee out of a caramel breeding, though obviously it is a risk. I don't know what percentage of caramels actually come out kinked; I would be curious to hear that statistic.

I started the poll because I'm seriously wrestling with whether to nix my spider projects. My female spider started out as a perfect baby, but as she's aged she's become more and more neurologic. She still eats like a champ and oddly, stops spinning or spazzing if I pick her up. She also has a perfect righting reflex. It's a very weird defect, but it just kind of bothers me to watch her ... And I feel as though if it bothers me that much, I shouldn't breed her (or my two spider combo males).

Then again, when I pick any of them up to interact with, they look and act like totally normal, healthy snakes. It's just that sometimes ... They spin.

I forgot to mention the pearl and regular woma wobble. (For those that don't know, the homozygous hidden gene woma, AKA pearl, is a pale ball python that apparently becomes severely neurologic shortly after hatching, fails to eat, and almost invariably dies.) I also forgot to add the sable; I'll see if I can put that in. To my knowledge, some sable combos also have issues (sable x spider is said to be lethal -- they are born, then fail and die -- and I think sable x champagne is also neurologic).