yes, that'd be a spectacular combo, and goes by the name Queen Bee. You have a 1/4 chance at each egg being a queen bee with breeding super pastel x lesser+spider

Personally I like to shoot for homozygous (aka super) pastel combos. Like I mentioned, if you pair your super pastel female with a lemon blast male, you have a good shot at a SUPER blast, which is one awesomely yellow animal.

Additionally, if you paired the super pastel female with ANY pastel-combo male, you have a good shot at a combo that includes super pastel. Pair her with a bumblebee, and you can hit the killer bee. Pair her with a pastel lesser, and you can hit the super pastel lesser. Pair her with a firefly, and you can get the superfly (I think that's what a super pastel fire is called). Get the trend here? lol. I LOVE combos that include super pastel.