I don't think their size or handle-ability should be an issue for you. As far as keeping a boa in the same room as your balls....I'd QT the heck out of it first. For at least three months. And I'd probably seriously consider getting an inexpensive normal ball python to keep in an enclosure right next to the boa's QT. This is because even after three months, a boa may show no signs of carrying IBD, but you don't want to risk exposing your ball pythons to that....even if the risk of it being there is very small.
If you expose one ball python to the boas environment (not the same enclosure!)....and it survives without any ill effects for three months...then you can be pretty confident that the rest of your balls would be safe in the same room with it.
This may be a case of my over-protective-motherhood-self being extra cautious...but I couldn't let a thread like this go by without mentioning these cautions. Good luck with whatever you choose to do!
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