There have been plenty of 4 or more gene combo's produced. That's not including having supers as part of the count.

Off the top of my head real quick, these breeders have produced some:
NERD
BHB
Brock Wagner
Marcus Jayne
Collin Weaver
Corey Woods
I'm sure there are more that I'm missing but like I said, that's just off the top of my head real quick.