Well to tie this in to the original post....breeding a German Shepherd who is known to carry the gene for Hip Displaysia is considered unethical.
It is something that "back yard" breeders do all the time and one of the reasons you would be encouraged to buy only from a reputable breeder and not a puppy mill.
A reputable breeder will go a long way to make sure his stock doesnt carry the gene's for the defact, including having his dogs x-rayed and certified to not have the disease.
Also there is the question...how many of the genetic pure bred dog diseases were caused by breeders doing things they shouldnt have been doing, like inbreeding and breeding animals with known defects?
To be humane you have a responsibility to the animal. You would not want to intentionally pass along traits that in the end could harm the animals quality of life.
Not saying the wobble does this in a Spider. But if it did then it is equiv to hip displasia in dogs and would be unethical to breed an animal who had it.