You certainly can feed multiple mice per feeding. I've been feeding mine f/t small rats but I got tired of the dessicated, smashed rats I'd been getting and did live the last feed. Couldn't bring myself to kill a rat so I bought 2 large male mice. My BP did just fine with the two. Was kind of funny, he thought feeding time was over and went back in his hide after the first one, but was quite interested in eating the second once I tossed it in.