It's different for everybody. The average reaction is an itching sensation especially around sensitive parts of the face (lips, eyes, noes). Some people don't react to it at all. For me, it's pretty uncomfortable but not unbearable. I just make sure to keep my face away and I always wash me hands after handling any of my hair kickers. Even if I do get some of those hairs on my face some warm water and soap seems to do the trick.

It can be mildly irritating but it seems a small price to pay for such a beautiful animal.