Absolutely. I don't use the word "chase" per say, but I have been charged by a couple PO-ed cottonmouths. They don't just stand in S-position waiting for you to get close when they feel threatened, they come at you a couple feet at a time, position, stare you down, charge a few feet again.
Granted the couple of times it happened, I gave the snake more than enough reason to be pissed off (stepped on a log that the snake was hiding under, almost stepped on a near-invisible mud-covered snake itself more than once)
I don't know if they would have actually tagged me, but they put on a very aggressive show to try to scare you off. They are the ONLY snake I know to actually move TOWARDS a human when they feel threatened. Most snakes pose, hiss, and try to run away.