No snake is trust worthy. No if, ands, or buts. They're not domesticated animals, and do not recognize us as "family" or part of your group in the way a companion animal would.... It would be a very painful mistake to think otherwise. There are some tolerances when you consider the snakes size, strength, toxicity (if it is venomous) etc.
The Scrubs I've kept were all bar necks, and were definitely the sharpest pythons I've dealt with, hands down. They watch your every move...turn their head and all when you shift. They aim for facial strikes unless you try and restrain them, when they do get agitated.
Don't under estimate their strength either. For being the most slender giant Python, they can reaaaally put up a fight. They have some KO power to them. Trust me.