DNA, Chromosomes and Chimera talk

My point was not that this animal was in fact a hybrid just that there is a possibility, if not very small, of the animal the vet described could exist in real life. An exercise in pointlessness? Possibly, but interesting to me at least. Truthfully I do not believe any trained vet would say this even if they didn't know much about snakes, and I am not saying your acquaintance is a liar either. I think this is more likely due to a miscommunication, as I said earlier. Let her know she is welcome and that we all had to start somewhere.

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Originally Posted by AntTheDestroyer

My point was not that this animal was in fact a hybrid just that there is a possibility, if not very small, of the animal the vet described could exist in real life. An exercise in pointlessness? Possibly, but interesting to me at least. Truthfully I do not believe any trained vet would say this even if they didn't know much about snakes, and I am not saying your acquaintance is a liar either. I think this is more likely due to a miscommunication, as I said earlier. Let her know she is welcome and that we all had to start somewhere.

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so, just out of curiosity...would the poodle/bulldog scenario be possible, just in theory ?

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Originally Posted by zina10

so, just out of curiosity...would the poodle/bulldog scenario be possible, just in theory ?

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I am not going to say it is impossible, but certainly even less likely. Some of the processes I am referring to only apply to hybrids of different species, which a poodle and a bulldog are not. Truthfully I am not as well versed on dog genetics.

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Originally Posted by AntTheDestroyer

I am aware the genetics are mixed code from each parent in a chimera, but phenotypic expression is not necessarily. Phenotype is what we are talking about in this situation, no? I explained my train of thought with different looking siblings being combined into a chimera, so I am not sure why you are still bringing up mixed genetic code. Am I missing something?

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I bring it up because I have yet to see hybrids in the animal kingdom where one species completely dominants over the other as being suggested. Even if there is, there's plenty of super balls that show what to expect, even the one you just posted.

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Originally Posted by AntTheDestroyer

It could be that no one is advertising the more plain hatchlings. Here is a mix that is exactly opposite of what you have described head of a blood, pattern of a ball. http://s218.photobucket.com/user/abi...rball.jpg.html

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The picture is too low quality to pick out any features but even looking through the grain the head shape (I should of been more specific) looks more ball than blood to me. And even at that low quality it is still very obvious it is a hybrid even just looking at the body.

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Originally Posted by AntTheDestroyer

Diploid means two chromosomes, one from each parent containing genetic code or DNA. Each chromosome is composed of two strands of DNA so that means four DNA to a set. Polyploid is having more than a single set from each parent, usually double so 4 chromosomes or 8 strands of DNA. Out of the 4 one matching pair is allowed to pair during meiosis creating essentially cloned DNA, but each chromosome pair is not from the same parent. It may be unlikely that this is possible because it is thought that homoploid hybrids are more common in animals, but not many studies have been done on hybrid genetics in animals.

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I still don't see how this give the possibility suggested.

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Originally Posted by AntTheDestroyer

My point was not that this animal was in fact a hybrid just that there is a possibility, if not very small, of the animal the vet described could exist in real life.

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Ant,

Reading all of your replies it seems you are somewhat confused about how the genetics of chimeras work even after OWAL's attempts to clear it up. Perhaps I might have more success.

First off, no, it is absolutely not possible for an animal like the vet described to exist and I say that with absolute certainty. You cannot have a hybrid that is genetically/phenotypically ball python on the outside and genetically/phenotypically blood python on the inside.

A chimera comes about from the the fusion of two embryos in the womb. The embryos have different genotypes and so, when a chimera is sampled by both skin sample and blood sample, the two samples come back as being different. However, both samples come back as being from the same mother and father, which is to say the samples look like they came from siblings, despite the fact that they came from a single individual. The samples do not come back looking like two wholly unrelated entities.

So... If you had a ball/blood hybrid and if it were a chimera, it would look exactly like a normal ball/blood hybrid on the outside and on the inside and the only way you could tell it was a chimera would be by genetic testing and not by popping it.

Truthfully how many super ball clutches have you seen? Here is one that could be easily confused for a ball by someone with little experience http://i878.photobucket.com/albums/a...pslkyghga6.jpg
I have seen some T. radix hybrids that look exactly like their parent, and isn't this the thing the entire anti hybrid crowd base their hysteria off of? In a polyploid situation you end up with the genetic information translated my mieosis from that specific pair is an exact copy of the parents dna. If the chromosome that codes for exterior looks is ball and the chromosome that codes for internal organs is blood then you end up with the situation the vet described. We are talking about a very specific combination that would likely not pop up often, and in general you would end up with animals that is a mix of the species.

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Originally Posted by OhhWatALoser

Perhaps we should dial back to the original topic, what is the difference between ball and blood genitalia?

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I hear you and I admit that I don't know much about snake genitalia. It seems pretty hard to find pictures of blood python hemipenes. I think it would more strange if they were identical based off my experience with biology.

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Originally Posted by AntTheDestroyer

Truthfully how many super ball clutches have you seen? Here is one that could be easily confused for a ball by someone with little experience http://i878.photobucket.com/albums/a...pslkyghga6.jpg
I have seen some T. radix hybrids that look exactly like their parent, and isn't this the thing the entire anti hybrid crowd base their hysteria off of? In a polyploid situation you end up with the genetic information translated my mieosis from that specific pair is an exact copy of the parents dna. If the chromosome that codes for exterior looks is ball and the chromosome that codes for internal organs is blood then you end up with the situation the vet described. We are talking about a very specific combination that would likely not pop up often, and in general you would end up with animals that is a mix of the species.


I hear you and I admit that I don't know much about snake genitalia. It seems pretty hard to find pictures of blood python hemipenes. I think it would more strange if they were identical based off my experience with biology.

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This isn't a situation involving polyploidy. As far as we know all snakes have 36 pairs of chomosomes: 20 micro, 36 macro. Hybrids between python species occur successfully so often because of the similarities. Many of them are even fertile.

And its not the chromosome as one whole that codes for traits, its the alleles on the chromosomes that do. There are very many alleles that go into each trait that an organism possesses. Some hybrids may look more or less like one of the parents, but that goes for any organism, including those that are not hybrids.

And its highly likely that most python species have very similar hemipenes. Given that many can interbreed successfully and produce fertile offspring the reproductory organs must be similar.

I hope that this made some sense. If any of it is unclear or anybody has a question let me know!


Sent from my iPhone using Tapatalk

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Originally Posted by asplundii

Ant,

Reading all of your replies it seems you are somewhat confused about how the genetics of chimeras work even after OWAL's attempts to clear it up. Perhaps I might have more success.

First off, no, it is absolutely not possible for an animal like the vet described to exist and I say that with absolute certainty. You cannot have a hybrid that is genetically/phenotypically ball python on the outside and genetically/phenotypically blood python on the inside.

A chimera comes about from the the fusion of two embryos in the womb. The embryos have different genotypes and so, when a chimera is sampled by both skin sample and blood sample, the two samples come back as being different. However, both samples come back as being from the same mother and father, which is to say the samples look like they came from siblings, despite the fact that they came from a single individual. The samples do not come back looking like two wholly unrelated entities.

So... If you had a ball/blood hybrid and if it were a chimera, it would look exactly like a normal ball/blood hybrid on the outside and on the inside and the only way you could tell it was a chimera would be by genetic testing and not by popping it.

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No I am aware that a chimera is a fusion of two embryos, which is why I said "As we see in snakes you can actually get offspring that resemble each parent, which is why I went with the chimera theory". Meaning that it could be a Chimera between two phenotypically opposite animals. I think OWAL caught this. After thinking about it more I was over complicating the possibility and there are even other ways you can create this snake. Speaking in absolutes is neither scientific or advisable. As I already told OWAL I am aware is comprised of genetic material of both parents but that does not mean it will share the phenotype of both or either.

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Originally Posted by Yamitaifu

This isn't a situation involving polyploidy. As far as we know all snakes have 36 pairs of chomosomes: 20 micro, 36 macro. Hybrids between python species occur successfully so often because of the similarities. Many of them are even fertile.

And its not the chromosome as one whole that codes for traits, its the alleles on the chromosomes that do. There are very many alleles that go into each trait that an organism possesses. Some hybrids may look more or less like one of the parents, but that goes for any organism, including those that are not hybrids.

And its highly likely that most python species have very similar hemipenes. Given that many can interbreed successfully and produce fertile offspring the reproductory organs must be similar.

I hope that this made some sense. If any of it is unclear or anybody has a question let me know!


Sent from my iPhone using Tapatalk

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You are probably right polyploidy is unlikely but until it is proven that this mechanism is not the way snake hybrids are created it still is a possibly. The number of chromosomes a parent species has does not effect if the hybrid is formed by homoploid or polyploid processes. I believe in some polyploid situations after meiosis the number of chromosome is returned to the same amount as the two parent species, that is of course if they have the same number. Again it is unlikely that it is polyploidy but I am not certain the research exists to say how hybrid snakes are formed to say one way or another.

A chromosome carries the DNA that hold an allele from parent to offspring. We are talking about the inheritance of said trait so the chromosome is molecule I am focused on. I can not explain every minute detail about the entire genetic science, nor do people want to listen to that.