Question on the use of the term "incompatible"

How exactly are breeders using the term "incompatible" in reference to specific lines? As a geneticist I know of two uses for it.

So, in terms of ball morphs just to keep it simple I will use the VPI axanthic and Jolliff axanthic lines.

Both are phenotypic axanthic

So, if I cross a VPI to a Jolliff do I get:

1) A bunch of normal looking offspring (that are in essence double het for both VPI and Jolliff.)? In this case incompatible would mean that the two lines are likely distinct genetic loci so even though there are 2 copies of an axanthic-type gene in each of the offspring the offspring are normal appearing because the 2 axanthic-type genes are are at different locations and therefore each is complimented by the normal WT copy at the same location.

2) No viable offspring? In this case incompatible would quite literally mean the 2 different mutations are not compatible when present in the same animal as single copies leading to the death of the offspring

I'm pretty sure it is used in terms of #1.

There are no ball pythons traits that when combined have been proven an always fatal combination... to my knowledge.

The answer is #1

Justin

Quote:

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Originally Posted by jkobylka

There are no ball pythons traits that when combined have been proven an always fatal combination... to my knowledge.

The answer is #1

Justin

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actually theres a combination with woma thats always fatal i forget the name tho

Quote:

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Originally Posted by jere000

actually theres a combination with woma thats always fatal i forget the name tho

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I think you may be thinking of the Pearl. But its the Homozygous from of the woma and not a combo.

Thank you all. I suspected #1 to be the case but I had not heard anything explicit on the matter and was just curious.

So, tangent, has anyone ever tried for a double homozygous VPI/Jolliff (or VPI/TSK or Jolliff/TSK)? I'd think maybe a double axanthic might hold its colour better over time...

Quote:

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Originally Posted by asplundii

Thank you all. I suspected #1 to be the case but I had not heard anything explicit on the matter and was just curious.

So, tangent, has anyone ever tried for a double homozygous VPI/Jolliff (or VPI/TSK or Jolliff/TSK)? I'd think maybe a double axanthic might hold its colour better over time...

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Mike Jolliff (originator of the Jolliff line Axanthic) did breed VPI line to Jolliff line years ago, and proved the incompatibility. However, I do not know if Mikie ever tried to produce the Homozygous combination). I do not know of anyone that has bred DH x DH, to see the outcome of the Double Homozygous animal.

I hope that helps,

Hey Tim,

Thanks for the info. Not a huge deal to me if it has happened or not, was just a moment of curiosity.

Cheers