Brian has been breeding scaleless snakes (colubrids) for years. I've held a couple. They're very hardy snakes that feel wickedly cool to hold. They're not at all delicate like people seem to think they should be.
Now...whether or not this particular genetic mutation will present other health risks for ball pythons remains to be seen. But it's an exciting first step to find out if a scaleless ball python can be just as hardy as a scaleless corn snake. Won't know until it's tried, and that's what Brian has stumbled onto.
Brian is one of a handful of individuals I would trust to work on a project like this in the right way. The well being of the animal is paramount in his heart. I'm confident of his abilities to recognize and care for an animal that is destined not to thrive, should that turn out to be the case, and I'm confident he wouldn't continue to breed an a truly weak animal simply for the sake of potential profit.
It'll be exciting to watch and see what happens with these new babies!