Increasing ventilation, if possible, would naturally be a best bet. My hunch is that if the substrate is dry and the water dish is reasonably small (not too small, you want the little guy to be able to find it) and temps are good, you won't have a problem. If you are using 3 inches of aspen bedding, then your snake will most likely spend a lot of time undernieth it. If the animal is under an inch or two of dry aspen on the warm side, and the water dish is on the opposite side of the heat, I wouldn't be too worried personally.
The health problems you'll notice from humidity that is too high will likely be apparent skin problems, blistering and discoloration. This would be from chronic damp or unclean conditions or inadequate ventilation--nothing you want to see, but not something you hear a whole lot about from careful hognose snake keepers either.
best of luck,
Adam
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