I actually worry more if my any of my ball pythons are constantly roaming their enclosure when they normally are happily snuggled away in a hide. It causes me to re-check their enclosure to find out what has them so disconcerted.
It's the nature of a ball python to be quiet and hidden away during the daytime and out casually exploring in the late evening (usually after I've gone to bed).
If your ball python is training for the snake olympics - it's probably stressed out by some stimulus in its enviroment.